discomfort in the center of your chest that lasts for more than a few minutes, or that goes away and comes back.Get emergency help right away if you have any symptoms of a heart attack or stroke while using Opzelura, including: Increased risk of major cardiovascular events such as heart attack, stroke, or death have happened in people 50 years of age and older who have at least one heart disease (cardiovascular) risk factor and taking a medicine in the class of medicines called JAK inhibitors by mouth, especially in current or past smokers. Increased risk of major cardiovascular events.Tell your healthcare provider if you have ever had any type of cancer.Wear protective clothing when you are in the sun and use a broad-spectrum sunscreen. Limit the amount of time you spend in the sunlight. Your healthcare provider will regularly check your skin during your treatment. Some people have had skin cancers while using Opzelura.People taking JAK inhibitors by mouth have a higher risk of certain cancers including lymphoma and lung cancer, especially if they are a current or past smoker.Lymphoma and other cancers have happened in people taking a medicine in the class of medicines called JAK inhibitors by mouth.Opzelura may increase your risk of certain cancers by changing the way your immune system works. Increased risk of death has happened in people 50 years of age and older who have at least one heart disease (cardiovascular) risk factor and are taking a medicine in the class of medicines called JAK inhibitors by mouth. Increased risk of death due to any reason (all causes).If you get a serious infection, your healthcare provider may stop your treatment until your infection is controlled. Opzelura can make you more likely to get infections or make worse any infections that you have. burning when you urinate or urinating more often than usualĪfter starting Opzelura, call your healthcare provider right away if you have any symptoms of an infection.warm, red, or painful skin or sores on your body.Think you have an infection or have symptoms of an infection such as: Ask your healthcare provider if you do not know if you have lived in an area where these infections are common. These infections may happen or become more severe if you use Opzelura. live in an area, or have lived in an area, or have traveled to certain parts of the country (such as the Ohio and Mississippi River valleys and the Southwest) where there is an increased chance for getting certain kinds of fungal infections.have TB or have been in close contact with someone with TB.
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